Summary: Enzyme encapsulation in metal-organic frameworks (MOFs)/covalent-organic frameworks (COFs) provides advancement in biocatalysis. yet the structural basis underlying the catalytic performance is challenging to probe. Here. we present an effective protocol to determine the orientation and dynamics of enzymes in MOFs/COFs using site-directed spin labeling and electron paramagnet... https://spencertifieders.shop/product-category/vacuums/