Ferroptosis is a type of programmed cell death resulting from iron overload-dependent lipid peroxidation. and could be promoted by activating transcription factor 3 (ATF3). SIRT1 is an enzyme accounting for removing acetylated lysine residues from target proteins by consuming NAD+. but its role remains elusive in ferroptosis and activating ATF3. https://cosmeticssquadets.shop/product-category/ovulation-test/
SIRT1 activated by AROS sensitizes glioma cells to ferroptosis via induction of NAD+ depletion-dependent activation of ATF3
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